Effect of Experimental Hyperhomocysteinemia on Brain Methylation and Neurodegenerative Markers in Rats DISSERTATION
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Homocysteine has anti-inflammatory properties in a hypercholesterolemic rat model in vivo
Inflammation is a hallmark in many neurodegenerative diseases like Alzheimer's disease or vascular dementia. Cholesterol and homocysteine are both vascular risk factors which have been associated with dementia, inflammation and blood-brain barrier dysfunction. In previous studies we found that hypercholesterolemia but not hyperhomocysteinemia induced inflammation in rats in vivo. The aim of the...
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